《JNK信号通路新成员的遗传筛选和功能研究（精）同济博士论丛》首次阐明了癌基因Myc抑制JNK介导的肿瘤侵袭与细胞迁移的分子机制。此外，本文还揭示了Hippo信号通路调控JNK介导的细胞生长的分子机制。本研究不但进一步完善了果蝇体内JNK信号通路调控网络，揭示这些基因在调控细胞死亡，细胞迁移，细胞增殖及肿瘤发生中扮演的重要作用，更是为癌症等疾病的预防及治疗提供了新的参考和潜在药物靶点。
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