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Title details for The Song of the Cell by Siddhartha Mukherjee - Wait list

The Song of the Cell

An Exploration of Medicine and the New Human

by Siddhartha Mukherjee
Dennis Boutsikaris
Audiobook (Includes supplementary content)
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Winner of the 2023 PROSE Award for Excellence in Biological and Life Sciences and the 2023 Chautauqua Prize!

Named a New York Times Notable Book and a Best Book of the Year by The Economist, Oprah Daily, BookPage, Book Riot, the New York Public Library, and more!

In The Song of the Cell, the extraordinary author of the Pulitzer Prize–winning The Emperor of All Maladies and the #1 New York Times bestseller The Gene "blends cutting-edge research, impeccable scholarship, intrepid reporting, and gorgeous prose into an encyclopedic study that reads like a literary page-turner" (Oprah Daily).
Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christened them "cells."

The discovery of cells—and the reframing of the human body as a cellular ecosystem—announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer's dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumonia—all could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies.

Filled with writing so vivid, lucid, and suspenseful that complex science becomes thrilling, The Song of the Cell tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. Told in six parts, and laced with Mukherjee's own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimate—a masterpiece on what it means to be human.

"In an account both lyrical and capacious, Mukherjee takes us through an evolution of human understanding: from the seventeenth-century discovery that humans are made up of cells to our cutting-edge technologies for manipulating and deploying cells for therapeutic purposes" (The New Yorker).

  • Creators

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  • Awards

  • Release date

    October 25, 2022

  • Formats

    • OverDrive Listen audiobook

      • ISBN: 9781797147093
      • File size: 462531 KB
      • Duration: 16:03:36

  • Languages

    • English

  • Reviews

    • Publisher's Weekly

      Starred review from August 29, 2022
      A better understanding of the cell holds immense power for medicine according to this eye-opening account from Pulitzer winner Mukherjee (The Emperor of All Maladies). He begins with the ground-breaking realization from two 19th-century scientists that every bit of plant and animal tissue in the world is made up of microscopic cells. Since then, Mukherjee writes, there has been “a revolution in the making, and a history (and future) that had been unwritten: of cells, of our capacity to manipulate cells.” An extraordinarily gifted storyteller, Mukherjee offers an expansive chronology of discovery in cell therapies (such as IVF) and setbacks, such as the use of thalidomide for pregnancies in the 1960s. He also includes stories of what he calls “new humans”—Mukherjee clarifies that the term isn’t a sci-fi-inspired “vision of the future,” but rather everyday folks whose health has been restored by advances in cellular manipulation and engineering, such as a patient who recovered from leukemia with cell therapy. The author’s ideas about the near future of medicine (one in which medicine will “perhaps even create synthetic versions of cells, and parts of humans”) are both convincing and inspiring, and woven throughout his narrative are accessible explanations of cell biology and immunology. This is another winner from Mukherjee.

    • AudioFile Magazine
      This is the second of Mukherjee's audiobooks that Dennis Boutsikaris has narrated, after 2017's THE GENE. In this expansive history of the researchers who unlocked the mysteries of the cell, Boutsikaris demonstrates again the importance of an experienced narrator in shaping a complex narrative. Using many of his skills as a narrator of bestselling thrillers, Boutsikaris shades a syllable here, adds a degree of emphasis there, heightening and bringing dramatic tension to a history that is already skillfully told and highly accessible but, at times, unavoidably dense. This is a narrative to digest slowly, step by step. The chapters are conveniently brief, and it's no effort to listen to such an adept performer a second, even a third, time. D.A.W. © AudioFile 2022, Portland, Maine

Formats

  • OverDrive Listen audiobook

subjects

Languages

  • English

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